G Protein alpha z Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88111

Novus Biologicals, part of Bio-Techne
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NBP1-88111
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (98%), Rat (98%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all G Protein alpha z Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: YNAIDSLTRIIRALAALRIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFSRSSEYHLEDNAAYYLNDLERIAAADYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIF

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for G Protein alpha z Antibody

Immunohistochemistry-Paraffin: G Protein alpha z Antibody [NBP1-88111]

Immunohistochemistry-Paraffin: G Protein alpha z Antibody [NBP1-88111]

Immunohistochemistry-Paraffin: G Protein alpha z Antibody [NBP1-88111] - Analysis in human cerebral cortex and liver tissues. Corresponding G Protein alpha z RNA-seq data are presented for the same tissues.
Western Blot: G Protein alpha z Antibody [NBP1-88111]

Western Blot: G Protein alpha z Antibody [NBP1-88111]

Western Blot: G Protein alpha z Antibody [NBP1-88111] - Analysis in control (vector only transfected HEK293T lysate) and GNAZ over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunocytochemistry/ Immunofluorescence: G Protein alpha z Antibody [NBP1-88111]

Immunocytochemistry/ Immunofluorescence: G Protein alpha z Antibody [NBP1-88111]

Immunocytochemistry/Immunofluorescence: G Protein alpha z Antibody [NBP1-88111] - Staining of human cell line U-2 OS shows localization to vesicles. Antibody staining is shown in green.
View 4 more images

Applications for G Protein alpha z Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50-1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: G Protein alpha z

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. G protein z alpha, encoded by the GNAZ gene, is enriched in neural tissue and differs in sequence from other G alpha subunits. Alpha Subunits are encoded in 15 genes and several transcripts are alternatively spliced. Receptors may discriminate between splice variants; whether splice variants are functionally different in regulating effectors is not known. All alpha subunits appear to be palmitoylated near the N-terminus.

Alternate Names

G(x) alpha chain, guanine nucleotide binding protein (G protein), alpha z polypeptide, guanine nucleotide-binding protein G(z) subunit alpha, Gz-alpha, transducin alpha

Gene Symbol

GNAZ

Additional G Protein alpha z Products

Product Documents for G Protein alpha z Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for G Protein alpha z Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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