G6PC Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-31916

Novus Biologicals, part of Bio-Techne
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NBP2-31916
NBP2-31916-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all G6PC Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: MEEGMNVLHDFGIQSTHYLQVNYQDSQDWFIL

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (88%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for G6PC Antibody

Immunohistochemistry-Paraffin: G6PC Antibody [NBP2-31916]

Immunohistochemistry-Paraffin: G6PC Antibody [NBP2-31916]

Immunohistochemistry-Paraffin: G6PC Antibody [NBP2-31916] - Staining of human testis shows no cytoplasmic positivity in cells in seminiferous ducts as expected.
Immunohistochemistry-Paraffin: G6PC Antibody [NBP2-31916]

Immunohistochemistry-Paraffin: G6PC Antibody [NBP2-31916]

Immunohistochemistry-Paraffin: G6PC Antibody [NBP2-31916] - Staining of human duodenum shows moderate cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: G6PC Antibody [NBP2-31916]

Immunohistochemistry-Paraffin: G6PC Antibody [NBP2-31916]

Immunohistochemistry-Paraffin: G6PC Antibody [NBP2-31916] - Staining of human liver shows moderate cytoplasmic positivity in hepatocytes.

Applications for G6PC Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: G6PC

Glucose-6-phosphatase is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate. It is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Defects in the enzyme cause glycogen storage disease type I (von Gierke disease). [provided by RefSeq]

Alternate Names

EC 3.1.3.9, G6Pase, G-6-Pase, G6Pase-alpha, G6PT, glucose-6-phosphatase, Glucose-6-phosphatase alpha, glucose-6-phosphatase, catalytic (glycogen storage disease type I, von Gierkedisease), glucose-6-phosphatase, catalytic subunit, GSD1, GSD1a, MGC163350

Gene Symbol

G6PC1

UniProt

P35575 (Human)

Additional G6PC Products

Product Documents for G6PC Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for G6PC Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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