GABA-A R beta 1 Antibody
Novus Biologicals, part of Bio-Techne | Catalog # NB300-197
Key Product Details
Species Reactivity
Validated:
Mouse, Rat
Cited:
Mouse
Predicted:
Bovine (100%), Canine (100%), Chicken (100%), Human (100%), Primate (100%), Xenopus (100%), Zebrafish (100%). Backed by our 100% Guarantee.
Applications
Validated:
Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot
Cited:
Immunohistochemistry-Frozen
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Fusion protein from the cytoplasmic loop of the beta 1 subunit. Accession # P15431
Reactivity Notes
It is anticipated that the antibody will react with bovine, canine, chicken, human, mouse, non-human primate, Xenopus, and zebra fish based on the fact that these species have 100% homology with the amino acid sequence used as antigen.
Localization
Integral membrane protein
Specificity
Specific for the ~55 kDa beta 1-subunit of the GABA A receptor in Western blots.
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Theoretical MW
55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Scientific Data Images for GABA-A R beta 1 Antibody
![Western Blot: GABA-A R beta 1 Antibody [NB300-197]](https://resources.bio-techne.com/images/products/GABA-A-R-beta-1-Antibody-Western-Blot-NB300-197-img0005.jpg "Western Blot: GABA-A R beta 1 Antibody [NB300-197]")
Western Blot: GABA-A R beta 1 Antibody [NB300-197]
Western Blot: GABA-A R beta 1 Antibody [NB300-197] - Mouse whole brain lysates showing specificimmunolabeling of the ~55 kDa beta1-subunit of the GABAA-R.![Western Blot: GABA-A R beta 1 Antibody [NB300-197]](https://resources.bio-techne.com/images/products/GABA-A-R-beta-1-Antibody-Western-Blot-NB300-197-img0004.jpg "Western Blot: GABA-A R beta 1 Antibody [NB300-197]")
Western Blot: GABA-A R beta 1 Antibody [NB300-197]
Western Blot: GABA-A R beta 1 Antibody [NB300-197] - Rat cerebellar (Cb) and hippocampal (Hipp) lysates showing specific immunolabeling of the ~55k beta 1-subunit of the GABA-A R beta 1 Antibody.Applications for GABA-A R beta 1 Antibody
Application
Recommended Usage
Immunohistochemistry
1:10-1:500
Immunohistochemistry-Frozen
1:10-1:500
Immunohistochemistry-Paraffin
1:10-1:500
Western Blot
1:1000
Application Notes
This antibody is useful in Immunohistochemistry (PMID: 21628464). Use in Immunohistochemistry-Frozen reported in scientific literature (PMID 21628464)
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
Preservative
No Preservative
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at -20C. Avoid freeze-thaw cycles.
Background: GABA-A R beta 1
Long Name
gamma-Aminobutyric Acid Type A Receptor, beta-1 Polypeptide
Alternate Names
GABAAR beta 1, GABAARb1, GABRB1
Gene Symbol
GABRB1
UniProt
Additional GABA-A R beta 1 Products
Product Documents for GABA-A R beta 1 Antibody
Product Specific Notices for GABA-A R beta 1 Antibody
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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