GABA-AR alpha 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16565

Novus Biologicals, part of Bio-Techne
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NBP2-16565
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Key Product Details

Species Reactivity

Validated:

Human, Rat

Predicted:

Bovine (100%), Chicken (97%), Mouse (99%), Rabbit (100%), Rhesus Macaque (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GABA-A R alpha 1 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human GABA-AR alpha 1. The exact sequence is proprietary.

Reactivity Notes

Zebrafish (89%).

Localization

Cell junction; synapse; postsynaptic cell membrane; Multi-pass membrane protein; Cell membrane; Multi-pass membrane protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

52 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for GABA-AR alpha 1 Antibody

Western Blot: GABA-AR alpha 1 Antibody [NBP2-16565]

Western Blot: GABA-AR alpha 1 Antibody [NBP2-16565]

Western Blot: GABA-AR alpha 1 Antibody [NBP2-16565] - GABA A Receptor alpha 1 antibody detects GABA A Receptor alpha 1 protein by Western blot analysis. Various whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with GABA A Receptor alpha 1 antibody diluted by 1:500.
Immunohistochemistry-Paraffin: GABA-AR alpha 1 Antibody [NBP2-16565]

Immunohistochemistry-Paraffin: GABA-AR alpha 1 Antibody [NBP2-16565]

Immunohistochemistry-Paraffin: GABA-A R alpha 1 Antibody [NBP2-16565] - Paraffin-embedded rat brain. GABA A Receptor alpha 1 antibody [N1C1] diluted at 1:500.
Immunohistochemistry-Paraffin: GABA-AR alpha 1 Antibody [NBP2-16565]

Immunohistochemistry-Paraffin: GABA-AR alpha 1 Antibody [NBP2-16565]

Immunohistochemistry-Paraffin: GABA-A R alpha 1 Antibody [NBP2-16565] - Paraffin-embedded rat brain. GABA A Receptor alpha 1 antibody [N1C1] diluted at 1:500.

Applications for GABA-AR alpha 1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: GABA-A R alpha 1

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq]

Long Name

gamma-Aminobutyric Acid Type A Receptor, alpha-1 Polypeptide

Alternate Names

EJM, GABAAR alpha 1, GABAARa1, GABRA1

Gene Symbol

GABRA1

UniProt

P14867 (Human)

Additional GABA-A R alpha 1 Products

Product Documents for GABA-AR alpha 1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GABA-AR alpha 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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