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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # OTI1G9

Concentration

1 mg/ml

Product Specifications

Immunogen

Human recombinant protein fragment corresponding to amino acids 32-259 of human GABRA5(NP_000801) produced in E.coli.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for GABA-AR alpha 5 Antibody (OTI1G9)

Western Blot: GABA-AR alpha 5 Antibody (OTI1G9) [NBP2-45752]

Western Blot: GABA-AR alpha 5 Antibody (OTI1G9) [NBP2-45752]

Western Blot: GABA-A R alpha 5 Antibody (1G9) [NBP2-45752] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GABA-A R alpha 5.
Immunohistochemistry: GABA-AR alpha 5 Antibody (OTI1G9) [NBP2-45752]

Immunohistochemistry: GABA-AR alpha 5 Antibody (OTI1G9) [NBP2-45752]

Immunohistochemistry: GABA-A R alpha 5 Antibody (1G9) [NBP2-45752] - Analysis of Human endometrium tissue. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0)
Immunohistochemistry: GABA-AR alpha 5 Antibody (OTI1G9) [NBP2-45752]

Immunohistochemistry: GABA-AR alpha 5 Antibody (OTI1G9) [NBP2-45752]

Immunohistochemistry: GABA-A R alpha 5 Antibody (1G9) [NBP2-45752] - Analysis of Carcinoma of Human lung tissue.(Heat-induced epitope retrieval by Tris-EDTA, pH8.0) .

Applications for GABA-AR alpha 5 Antibody (OTI1G9)

Application
Recommended Usage

Immunohistochemistry

1:150

Western Blot

1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: GABA-A R alpha 5

GABA (A) receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA (A). Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics. GABA (A) Receptors are comprised of subunits and these are further classified into 3 major groups (alpha, beta, and gamma). The subunits determine the pharmacological characteristics.

Long Name

gamma-Aminobutyric Acid Type A Receptor, alpha-5 Polypeptide

Alternate Names

GABAAR alpha 5, GABAARa5, GABRA5

Gene Symbol

GABRA5

Additional GABA-A R alpha 5 Products

Product Documents for GABA-AR alpha 5 Antibody (OTI1G9)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GABA-AR alpha 5 Antibody (OTI1G9)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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