GABA-AR alpha 5 Antibody (S415-24) [Janelia Fluor® 549]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-59700JF549

Submit a review

Product Datasheet / COA / SDS

View Available Conjugates

Conjugate

Catalog #

Unconjugated

NBP2-59700

Alexa Fluor 405

NBP2-59700AF405

Alexa Fluor 488

NBP2-59700AF488

Alexa Fluor 647

NBP2-59700AF647

Alexa Fluor 700

NBP2-59700AF700

Biotin

NBP2-59700B

DyLight 350

NBP2-59700UV

DyLight 405

NBP2-59700V

DyLight 488

NBP2-59700G

DyLight 550

NBP2-59700R

DyLight 650

NBP2-59700C

DyLight 680

NBP2-59700FR

DyLight 755

NBP2-59700IR

FITC

NBP2-59700F

HRP

NBP2-59700H

Janelia Fluor 646

NBP2-59700JF646

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Janelia Fluor 549

Antibody Source

Monoclonal Mouse IgG₁ Clone # S415-24

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all GABA-A R alpha 5 Antibodies »

Product Specifications

Immunogen

Fusion protein amino acids 368-419 (last cytoplasmic domain before extracellular C-terminus) of human GABA A Receptor Alpha5.

Localization

Cell Junction , Synapse , Postsynaptic Cell Membrane , Cell Membrane

Specificity

Detects ~55kDa. Does not cross-react with GABA A Receptor Alpha2 or other GABA-A Receptors based on KO validation data.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Applications for GABA-AR alpha 5 Antibody (S415-24) [Janelia Fluor® 549]

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: GABA-A R alpha 5

GABA (A) receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA (A). Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics. GABA (A) Receptors are comprised of subunits and these are further classified into 3 major groups (alpha, beta, and gamma). The subunits determine the pharmacological characteristics.

Long Name

gamma-Aminobutyric Acid Type A Receptor, alpha-5 Polypeptide

Alternate Names

GABAAR alpha 5, GABAARa5, GABRA5

Gene Symbol

GABRA5

Additional GABA-A R alpha 5 Products

Product Documents for GABA-AR alpha 5 Antibody (S415-24) [Janelia Fluor® 549]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for GABA-AR alpha 5 Antibody (S415-24) [Janelia Fluor® 549]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews