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GABA-B R1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-52389

Novus Biologicals, part of Bio-Techne
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NBP1-52389

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Porcine, Bat, Bovine, Canine, Equine, Hamster, Monkey, Primate, Rabbit

Predicted:

Orangutan (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Synthetic peptide DRLSCDGSRVHLLYK from the C-terminus of human GABA-B R1 (NP_001461.1; NP_068703.1; NP_068704.2; NP_068705.2).

Epitope

DRLSCDGSRVHLLYK from the C-Terminus

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%).

Specificity

Human GABBR1. This antibody is expected to recognize reported isoforms a, b and c (NP_001461.1, NP_068703.1, NP_068704.2 resp.).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for GABA-B R1 Antibody

Immunohistochemistry-Paraffin: GABA-B R1 Antibody [NBP1-52389]

Immunohistochemistry-Paraffin: GABA-B R1 Antibody [NBP1-52389]

Immunohistochemistry-Paraffin: GABA-B R1 Antibody [NBP1-52389] - Analysis of anti-GABBR1 antibody with human brain, cortex at concentration 3.75 ug/ml.

Applications for GABA-B R1 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

3.75-5 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS (pH 7.3) and 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: GABA-B R1

The inhibitory neurotransmitter, GABA, acts through two ligand-gated channels, GABA A and GABA C receptors and GABA B, the latter of which acts through a G protein mechanism. GABA BR1 is one of two G-protein coupled receptors for GABAb that acts as a heteromeric assembly with GABA BR2.

Long Name

gamma-Aminobutyric Acid Type B Receptor Subunit 1

Alternate Names

GABABR1, GABBR1, Gb1, GPRC3A

Entrez Gene IDs

2550 (Human)

Gene Symbol

GABBR1

UniProt

Additional GABA-B R1 Products

Product Documents for GABA-B R1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GABA-B R1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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