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GADD34 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89800

Novus Biologicals, part of Bio-Techne
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NBP1-89800
NBP1-89800-25ul

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: QPGEDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGEAEPCP

Reactivity Notes

Use in Mouse reported in scientific publication (PMID: 32435966).

Localization

Endoplasmic reticulum

Marker

ER Stress Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

74 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for GADD34 Antibody

Immunohistochemistry-Paraffin: GADD34 Antibody [NBP1-89800]

Immunohistochemistry-Paraffin: GADD34 Antibody [NBP1-89800]

Immunohistochemistry-Paraffin: GADD34 Antibody [NBP1-89800] - Staining of human pancreas shows strong cytoplasmic positivity in both exocrine glandular cells and islet cells.

Applications for GADD34 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
IHC-P, Retrieval method: HIER pH6
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GADD34

GADD34 is a phosphatase whose expression is increased by exposure of cells to DNA damage or stress induced growth arrest. Induction is correlated with apoptosis following exposure to ionizing radiation.

Long Name

Protein phosphatase 1 regulatory subunit 15A

Alternate Names

PPP1R15A

Entrez Gene IDs

23645 (Human)

Gene Symbol

PPP1R15A

UniProt

Additional GADD34 Products

Product Documents for GADD34 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GADD34 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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