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GALE Antibody (6G10) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-59421

Novus Biologicals, part of Bio-Techne
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NBP2-59421-100ul
NBP2-59421-50ul

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 6G10

Format

BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

Recombinant human GALE (1-348aa) purified from E. coli

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for GALE Antibody (6G10) - BSA Free

Western Blot: GALE Antibody (6G10)BSA Free [NBP2-59421]

Western Blot: GALE Antibody (6G10)BSA Free [NBP2-59421]

Western Blot: GALE Antibody (6G10) [NBP2-59421] - Lane 1: MCF7 cell lysates, Lane 2: Jurkat cell lysates, Lane 3: A431 cell lysates, Lane 4: A549 cell lysates, Lane 5: HeLa cell lysates, Lane 6: HepG2 cell lysates
Immunocytochemistry/ Immunofluorescence: GALE Antibody (6G10) - BSA Free [NBP2-59421]

Immunocytochemistry/ Immunofluorescence: GALE Antibody (6G10) - BSA Free [NBP2-59421]

Immunocytochemistry/Immunofluorescence: GALE Antibody (6G10) [NBP2-59421] - Analysis of GALE in Hep3B cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human GALE antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).

Applications for GALE Antibody (6G10) - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100

Western Blot

1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4), 10% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GALE

GALE encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified.

Alternate Names

EC 5.1.3, EC 5.1.3.2, FLJ95174, FLJ97302, Galactowaldenase, short chain dehydrogenase/reductase family 1E, member 1, UDP-, UDP galactose-4'-epimerase, UDP-galactose 4-epimerase, UDP-galactose-4-epimerase, UDP-glucose 4-epimerase

Gene Symbol

GALE

Additional GALE Products

Product Documents for GALE Antibody (6G10) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GALE Antibody (6G10) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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