GAMT Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-14036

Novus Biologicals, part of Bio-Techne
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NBP2-14036
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GAMT Antibodies »

Product Summary for GAMT Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: DGILYDTYPLSEETWHTHQFNFIKNHAFRLLKPGGVLTYCNLTSWGELMKSKYSDITIMFEETQVP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GAMT Antibody

Western Blot: GAMT Antibody [NBP2-14036]

Western Blot: GAMT Antibody [NBP2-14036]

Western Blot: GAMT Antibody [NBP2-14036] - Analysis in human cell line HepG2.
Immunohistochemistry-Paraffin: GAMT Antibody [NBP2-14036]

Immunohistochemistry-Paraffin: GAMT Antibody [NBP2-14036]

Immunohistochemistry-Paraffin: GAMT Antibody [NBP2-14036] - Staining of human rectum shows no positivity in glandular cells as expected.
Immunohistochemistry-Paraffin: GAMT Antibody [NBP2-14036]

Immunohistochemistry-Paraffin: GAMT Antibody [NBP2-14036]

Immunohistochemistry-Paraffin: GAMT Antibody [NBP2-14036] - Staining of human liver shows weak to moderate cytoplasmic postivity in hepatocytes na moderate staining of bile canaliculi.
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Applications for GAMT Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50-1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GAMT

GAMT is encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene.

Alternate Names

EC 2.1.1.2, guanidinoacetate N-methyltransferase, PIG2, TP53I2

Gene Symbol

GAMT

Additional GAMT Products

Product Documents for GAMT Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GAMT Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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