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Gastrin-releasing Peptide R/GRPR Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS831

Novus Biologicals, part of Bio-Techne
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NLS831

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Porcine, Bat, Bovine, Canine, Hamster, Monkey, Primate

Predicted:

Rabbit (94%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

Product Specifications

Immunogen

Synthetic 17 amino acid peptide from 3rd cytoplasmic domain of human Gastrin-releasing Peptide R/GRPR.

Epitope

3rd cytoplasmic domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Equine (88%), Turkey (82%), Chicken (82%), Lizard (82%).

Specificity

Human GRPR. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ADAM28 (41%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for Gastrin-releasing Peptide R/GRPR Antibody - BSA Free

Immunohistochemistry-Paraffin: Gastrin-releasing Peptide R/GRPR Antibody - BSA Free [NLS831]

Immunohistochemistry-Paraffin: Gastrin-releasing Peptide R/GRPR Antibody - BSA Free [NLS831]

Immunohistochemistry-Paraffin: Gastrin-releasing Peptide/Bombesin/Neuromedin C Antibody [NLS831] - Analysis of anti-GRPR antibody with human colon.

Applications for Gastrin-releasing Peptide R/GRPR Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry

1:10 - 1:500

Immunohistochemistry-Paraffin

15-20 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: Gastrin-releasing Peptide R/GRPR

Gastrin-releasing peptide receptor (GRPR) is a Bombesin Receptor. In addition to its involvement in autism and mental retardation, GRPR may also play a role in the progression of cancer. Nicotine exposure induces an increase in GRPR expression in the lung Shriver et al. (2000). GRPR has been reported in brain, breast, colon, lung, lymph node, ovary, placenta, prostate, stomach, and uterus. It has also been shown to be expressed in several cancers, including those in breast, colon, lung, ovary, pancreas, and prostate.

Long Name

Gastrin-releasing Peptide Receptor

Alternate Names

Gastrin-releasing PeptideR, Gastrinreleasing PeptideR, GRPR

Entrez Gene IDs

NM_005314 (Human)

Gene Symbol

GRPR

UniProt

Additional Gastrin-releasing Peptide R/GRPR Products

Product Documents for Gastrin-releasing Peptide R/GRPR Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Gastrin-releasing Peptide R/GRPR Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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