GATA-4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-56566

Novus Biologicals, part of Bio-Techne
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NBP2-56566
NBP2-56566-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%), Rat (97%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GATA-4 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: PFDSPVLHSLPGRANPAARHPNLDMFDDFSEGRECV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GATA-4 Antibody

Immunocytochemistry/ Immunofluorescence: GATA-4 Antibody [NBP2-56566]

Immunocytochemistry/ Immunofluorescence: GATA-4 Antibody [NBP2-56566]

Immunocytochemistry/Immunofluorescence: GATA-4 Antibody [NBP2-56566] - Staining of human cell line U-2 OS shows localization to nuclear bodies.

Applications for GATA-4 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GATA-4

GATA4 is a 46 kDa member of the GATA family of zinc finger containing transcription factors that is involved in the development of cardiac hypertrophy and remodeling, and plays a critical role in regulating basal and agonist or stress induced gene expression in cardiac and smooth muscle cell types. GATA4 contains a conserved MAPK phosphorylation site at serine 105 within the transcriptional activation domain. Serine 105 of GATA4 is phosphorylated in response to agonist stimulation through MEK 1 ERK1 / 2, and weakly through JNK or p38 MAPKs.

Alternate Names

GATA4

Gene Symbol

GATA4

Additional GATA-4 Products

Product Documents for GATA-4 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for GATA-4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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