GATA2/3 Antibody (SR1901)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27691

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-27691-100ul
NBP3-27691-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1901

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all GATA2/3 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human GATA2/3 (Uniprot #: P23769/P23771)

Specificity

Detects endogenous levels of total GATA2/3

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

51 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for GATA2/3 Antibody (SR1901)

Immunohistochemistry-Paraffin: GATA2/3 Antibody (SR1901) [NBP3-27691] -

Immunohistochemistry-Paraffin: GATA2/3 Antibody (SR1901) [NBP3-27691] - Immunohistochemical analysis of paraffin-embedded mouse kidney

Western Blot: GATA2/3 Antibody (SR1901) [NBP3-27691] -

Western Blot: GATA2/3 Antibody (SR1901) [NBP3-27691] - Western blot analysis of GATA2/3 expression in K562 cell lysate.
GATA2/3 Antibody (SR1901)

Immunocytochemistry/ Immunofluorescence: GATA2/3 Antibody (SR1901) [NBP3-27691] -

Immunocytochemistry/ Immunofluorescence: GATA2/3 Antibody (SR1901) [NBP3-27691] - Immunofluorescent analysis of K562 cells using NBP3-27691 (green)

Applications for GATA2/3 Antibody (SR1901)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Immunoprecipitation

1:50

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 150mM NaCl, 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GATA2/3

The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers and their enhancer-binding proteins. Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes. GATA3 had been shown in the chicken to be an enhancer-binding protein containing a zinc finger domain. GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells or macrophages. GATA3 is abundantly expressed in the T-lymphocyte lineage and is thought to participate in T-cell receptor gene activation through binding to enhancers. Labastie et al. (1994) cloned the human gene and the 5-prime end of the mouse gene. The human gene comprises 6 exons distributed over 17 kb of DNA. Its 2 zinc fingers are encoded by 2 separate exons highly conserved with those of GATA1, but no other structural homologies between the 2 genes could be found.

Alternate Names

endothelial transcription factor GATA-2, FLJ45948, GATA binding protein 2, GATA-binding protein 2NFE1B, MGC2306

Gene Symbol

GATA2

Additional GATA2/3 Products

Product Documents for GATA2/3 Antibody (SR1901)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for GATA2/3 Antibody (SR1901)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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