GBA2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89251

Novus Biologicals, part of Bio-Techne
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NBP1-89251
NBP1-89251-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (90%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GBA2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: HDTADWKDLNLKFVLQVYRDYYLTGDQNFLKDMWPVCLAVMESEMKFDKDHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDKFSSILSRGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GBA2 Antibody

Immunocytochemistry/ Immunofluorescence: GBA2 Antibody [NBP1-89251]

Immunocytochemistry/ Immunofluorescence: GBA2 Antibody [NBP1-89251]

Immunocytochemistry/Immunofluorescence: GBA2 Antibody [NBP1-89251] - Staining of human cell line U-251 MG shows localization to nucleoplasm, cytosol & the Golgi apparatus. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: GBA2 Antibody [NBP1-89251]

Immunohistochemistry-Paraffin: GBA2 Antibody [NBP1-89251]

Immunohistochemistry-Paraffin: GBA2 Antibody [NBP1-89251] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells.

Applications for GBA2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GBA2

GBA2 encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides as endogenous compounds. Studies to determine subcellular localization of this protein in the liver indicated that the enzyme was mainly enriched in the microsomal fraction where it appeared to be confined to the endoplasmic reticulum. This putative transmembrane protein is thought to play a role in carbohydrate transport and metabolism. [provided by RefSeq]

Alternate Names

AD035, Beta-glucocerebrosidase 2, Beta-glucosidase 2, bile acid beta-glucosidase, DKFZp762K054, glucosidase, beta (bile acid) 2, Glucosylceramidase 2, KIAA1605EC 3.2.1.45, MGC16895, NLGase, non-lysosomal glucosylceramidase

Entrez Gene IDs

57704 (Human)

Gene Symbol

GBA2

UniProt

Q9HCG7 (Human)

Additional GBA2 Products

Product Documents for GBA2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GBA2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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