GCAP2 Antibody (A1) [Janelia Fluor® 646]

Novus Biologicals, part of Bio-Techne | Catalog # NB120-5422JF646

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NB120-5422AF350

Alexa Fluor 405

NB120-5422AF405

Alexa Fluor 488

NB120-5422AF488

Alexa Fluor 532

NB120-5422AF532

Alexa Fluor 594

NB120-5422AF594

Alexa Fluor 647

NB120-5422AF647

Alexa Fluor 700

NB120-5422AF700

Alexa Fluor 750

NB120-5422AF750

Biotin

NB120-5422B

CoraFluor 1

NB120-5422CL1

DyLight 350

NB120-5422UV

DyLight 405

NB120-5422V

DyLight 488

NB120-5422G

DyLight 550

NB120-5422R

DyLight 594

NB120-5422DL594

DyLight 650

NB120-5422C

DyLight 680

NB120-5422FR

DyLight 755

NB120-5422IR

FITC

NB120-5422F

HRP

NB120-5422H

Janelia Fluor 525

NB120-5422JF525

Janelia Fluor 549

NB120-5422JF549

Janelia Fluor 585

NB120-5422JF585

Janelia Fluor 635

NB120-5422JF635

Janelia Fluor 669

NB120-5422JF669

mFluor Violet 450 SE

NB120-5422MFV450

mFluor Violet 500 SE

NB120-5422MFV500

mFluor Violet 610 SE

NB120-5422MFV610

Forumulation

Catalog #

BSA Free

NB120-5422

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Bovine

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Janelia Fluor 646

Antibody Source

Monoclonal Mouse IgG_2A Clone # A1

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GCAP2 Antibodies »

Product Summary for GCAP2 Antibody (A1) [Janelia Fluor® 646]

Immunogen

Bacterial expressed full length GCAP-2.

Localization

Cell Membrane

Specificity

This is specific for GCAP 2 and does not react with other isotypes.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2A

Applications for GCAP2 Antibody (A1) [Janelia Fluor® 646]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: GCAP2

Guanylate cyclase-activating proteins (GCAPs) are calcium binding proteins that belong to the calmodulin superfamily. GCAPs without calcium are responsible for activation of photoreceptor guanylate cyclase during light adaptation. Studies have shown that the addition or subtraction of Ca2+ results in major conformational changes and the activation/deactivation of GCAP 1 and GCAP 2. It has been demonstrated that both GCAP 1 and 2 act on guanylate cyclase similarly and have approximately 50% homology between the two forms. GCAP-1 is predominantly localized in the photoreceptor outer segments, while GCAP 2 is found in retina samples.

Alternate Names

DKFZp686E1183, GCAP 2, GCAP2guanylate cyclase-activating protein, photoreceptor 2, Guanylate cyclase activator 1B, guanylate cyclase activator 1B (retina), guanylyl cyclase-activating protein 2, GUCA2, RP48

Gene Symbol

GUCA1B

Additional GCAP2 Products

Product Documents for GCAP2 Antibody (A1) [Janelia Fluor® 646]

Product Datasheets

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COA

SDS

Product Specific Notices for GCAP2 Antibody (A1) [Janelia Fluor® 646]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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