GCAP3 Antibody (3F10)

Novus Biologicals, part of Bio-Techne | Catalog # H00009626-M03

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunoprecipitation, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 3F10

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GCAP3 Antibodies »

Product Specifications

Immunogen

GUCA1C (NP_005450.2, 110 a.a. ~ 209 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. KNKLLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLRVICNGKQPDMETDSSKSPDKAGLGKVKMK

Specificity

GUCA1C - guanylate cyclase activator 1C (3F10)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for GCAP3 Antibody (3F10)

Sandwich ELISA: GCAP3 Antibody (3F10) [H00009626-M03] - Detection limit for recombinant GST tagged GUCA1C is 0.3 ng/ml as a capture antibody.
Immunoprecipitation: GCAP3 Antibody (3F10) [H00009626-M03]

Immunoprecipitation: GCAP3 Antibody (3F10) [H00009626-M03]

Immunoprecipitation: GCAP3 Antibody (3F10) [H00009626-M03] - Analysis of GUCA1C transfected lysate using anti-GUCA1C monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with GUCA1C rabbit polyclonal antibody.

Applications for GCAP3 Antibody (3F10)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: GCAP3

GCAP3, also known as GUCA1C or Guanylyl cyclase-activating protein 3, has a 209 amino acid isoform that is 24 kDa and a short 196 amino acid isoform that is approx. 22 kDa; commonly found in retina; in conditions of low free calcium ions concentration stimulates guanylyl cyclase 1 (GC1) and GC2 and when the concentration is elevated inhibits guanylyl cyclases, which is very important for the recuperation of the dark state of rod photoreceptors following light exposure. Disease research has linked this protein with cone dystrophy, neuronitis, and retinitis. This protein has shown interactions with GUCA1A, GUCA1B, GUCY2D, GUCY2F, and CNGA3 proteins in the pathways such as the visual cycle in retinal rods, olfactory transduction, and phototransduction pathways.

Alternate Names

GCAP3GCAP 3, guanylate cyclase activator 1CMGC120159, guanylyl cyclase-activating protein 3, MGC120158

Entrez Gene IDs

9626 (Human)

Gene Symbol

GUCA1C

UniProt

NP_005450 (Human)

Additional GCAP3 Products

Product Documents for GCAP3 Antibody (3F10)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for GCAP3 Antibody (3F10)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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