GDAP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-84963

Novus Biologicals, part of Bio-Techne
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NBP2-84963-0.1ml
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

View all GDAP1 Antibodies »

Product Specifications

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of GDAP1. Peptide sequence: ETELQRRNEETPEEGQQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWG The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for GDAP1 Antibody

Western Blot: GDAP1 Antibody [NBP2-84963]

Western Blot: GDAP1 Antibody [NBP2-84963]

Western Blot: GDAP1 Antibody [NBP2-84963] - WB Suggested Anti-GDAP1 Antibody. Titration: 1.0 ug/ml. Positive Control: OVCAR-3 Whole Cell

Applications for GDAP1 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GDAP1

The GDAP1 gene encodes for a member of the ganglioside-induced differentiation-associated protein family that is active in signal transduction pathways during neuronal development. These proteins also monitor the mitochondrial network by endorsing mitochondrial fission. Isoform 1 is 358 amino acids long at 41 kDA while isoform 2 is 290 amino acids long at approximately 33 kDA. Neuropathy, muscular dystrophy, and multiple forms of Charcot-Marie-Tooth Disease have been linked to mutations in the GDAP1 gene. The GDAP1 gene is involved in NgR-p75(NTR)-Mediated signaling and interacts with genes such as FIS1, ATP6V1D, TUBB, UBC, and YWHAB.

Alternate Names

Charcot-Marie-Tooth neuropathy 4A, CMT2K, CMT4, CMT4A, CMTRIA, ganglioside differentiation associated protein 1, ganglioside-induced differentiation-associated protein 1, truncated ganglioside differentiation associated protein 1

Gene Symbol

GDAP1

Additional GDAP1 Products

Product Documents for GDAP1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GDAP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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