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GDF-11/BMP-11 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-57399

Novus Biologicals, part of Bio-Techne
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NBP2-57399
NBP2-57399-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: DFKQVLHSWFRQPQSNWGIEINAFDPSGTDLAVTSLGPGAEGLHPFMELRVLENT

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GDF-11/BMP-11 Antibody

Western Blot: GDF-11/BMP-11 Antibody [NBP2-57399]

Western Blot: GDF-11/BMP-11 Antibody [NBP2-57399]

Western Blot: GDF-11/BMP-11 Antibody [NBP2-57399] - Analysis in human cell line RT-4, human cell line U-251 MG, human plasma, human liver tissue and human tonsil tissue.
Immunohistochemistry-Paraffin: GDF-11/BMP-11 Antibody [NBP2-57399]

Immunohistochemistry-Paraffin: GDF-11/BMP-11 Antibody [NBP2-57399]

Immunohistochemistry-Paraffin: GDF-11/BMP-11 Antibody [NBP2-57399] - Staining of human testis shows moderate cytoplasmic positivity in Leydig cells.
Immunohistochemistry-Paraffin: GDF-11/BMP-11 Antibody [NBP2-57399]

Immunohistochemistry-Paraffin: GDF-11/BMP-11 Antibody [NBP2-57399]

Immunohistochemistry-Paraffin: GDF-11/BMP-11 Antibody [NBP2-57399] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in glial cells.

Applications for GDF-11/BMP-11 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GDF-11/BMP-11

BMP11 is encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.

Long Name

Growth Differentiation Factor 11

Alternate Names

BMP-11, BMP11, GDF11

Gene Symbol

GDF11

Additional GDF-11/BMP-11 Products

Product Documents for GDF-11/BMP-11 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GDF-11/BMP-11 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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