Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%). Backed by our 100% Guarantee.

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all GDF-6/BMP-13 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of the human GDF6. The immunogen is located within amino acids 320 - 370 of GDF6. Amino Acid Squence: AFASRHGKRHGKKSRLR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GDF-6/BMP-13 Antibody - BSA Free

Western Blot: GDF-6/BMP-13 AntibodyBSA Free [NBP1-76364]

Western Blot: GDF-6/BMP-13 AntibodyBSA Free [NBP1-76364]

Western Blot: GDF-6/BMP-13 Antibody [NBP1-76364] - SK-N-SH lysate with GDF6 antibody at (A) 0.5 and (B) 1 ug/mL.

Applications for GDF-6/BMP-13 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

0.5-1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GDF-6/BMP-13

Growth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. Both GDF6 and GDF7 are closely related to GDF5 which has been shown to induce activation of plasminogen activator, thereby inducing angiogenesis. It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation. In Xenopus, GDF6 is expressed at the edge of the neural plate and within the anterior neural plate including the eye fields. GDF6 is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. It may regulate patterning of the ectoderm by interacting with bone morphogenetic proteins (BMPs), and control eye development. Mutations in this gene result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), a congenital disorder of spinal segmentation.

Long Name

Growth Differentiation Factor 6

Alternate Names

BMP-13, GDF6

Gene Symbol

GDF6

UniProt

NP_001001557 (Human)

Additional GDF-6/BMP-13 Products

Product Documents for GDF-6/BMP-13 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for GDF-6/BMP-13 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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