GDF-6/BMP-13 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-91934

Novus Biologicals, part of Bio-Techne
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NBP1-91934
NBP1-91934-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Mouse (91%), Rat (91%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation

Cited:

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GDF-6/BMP-13 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: IYRTYSIAEKLGINASFFQSSKSANTITSFVDRGLDDLSHTPLRRQKYLFDVSMLSDKEELVGAELRLFRQAPSAPWGPPAGPLHVQLF

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GDF-6/BMP-13 Antibody

Immunocytochemistry/ Immunofluorescence: GDF-6/BMP-13 Antibody [NBP1-91934]

Immunocytochemistry/ Immunofluorescence: GDF-6/BMP-13 Antibody [NBP1-91934]

Immunocytochemistry/Immunofluorescence: GDF-6/BMP-13 Antibody [NBP1-91934] - Staining of human cell line LHCN-M2 shows localization to nucleoplasm, nuclear membrane & vesicles. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: GDF-6/BMP-13 Antibody [NBP1-91934]

Immunohistochemistry-Paraffin: GDF-6/BMP-13 Antibody [NBP1-91934]

Immunohistochemistry-Paraffin: GDF-6/BMP-13 Antibody [NBP1-91934] - Staining of human stomach, lower shows strong membranous and cytoplasmic positivity in glandular cells.

Applications for GDF-6/BMP-13 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Immunoprecipitation

Reported in scientific literature (PMID:33147457)
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation/Permeabilization: PFA/Triton X-100
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GDF-6/BMP-13

GDF6 encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily of secreted signaling molecules. It is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), which is a congenital disorder of spinal segmentation. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Long Name

Growth Differentiation Factor 6

Alternate Names

BMP-13, GDF6

Gene Symbol

GDF6

Additional GDF-6/BMP-13 Products

Product Documents for GDF-6/BMP-13 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GDF-6/BMP-13 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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