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GEFT Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-54351

Novus Biologicals, part of Bio-Techne
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NBP1-54351

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Synthetic peptides corresponding to GEFT(RhoA/RAC/CDC42 exchange factor) The peptide sequence was selected from the C terminal of GEFT. Peptide sequence RLGDQAQGSTHTPINGSLPSLLLSPKGEVARALLPLDKQALGDIPQAPHD. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

64 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for GEFT Antibody

Western Blot: GEFT Antibody [NBP1-54351]

Western Blot: GEFT Antibody [NBP1-54351]

Western Blot: GEFT Antibody [NBP1-54351] - Titration: 0.2-1 ug/ml, Positive Control: Human brain.

Applications for GEFT Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GEFT

The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange.The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange (Souchet et al., 2002 [PubMed 11861769]).[supplied by OMIM].

Alternate Names

GEFTRAC/CDC42 exchange factor, Guanine nucleotide exchange factor GEFT, p63RhoGEFrho guanine nucleotide exchange factor 25, Rac/Cdc42/Rho exchange factor GEFT, Rho guanine nucleotide exchange factor (GEF) 25, RhoA/RAC/CDC42 exchange factor, RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT

Gene Symbol

ARHGEF25

UniProt

Additional GEFT Products

Product Documents for GEFT Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GEFT Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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