Geminin Antibody (S08-1F8)
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19484
Recombinant Monoclonal Antibody
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
Unconjugated
Antibody Source
Recombinant Monoclonal Rabbit IgG Clone # S08-1F8
Concentration
0.3 mg/ml
Product Specifications
Immunogen
Recombinant protein of human Geminin (Uniprot # O75496)
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG
Theoretical MW
24 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Scientific Data Images for Geminin Antibody (S08-1F8)
Western Blot: Geminin Antibody (S08-1F8) [NBP3-19484]
Western Blot: Geminin Antibody (S08-1F8) [NBP3-19484] - Western blot detection of Geminin in Jurkat cell lysates using NBP3-19484 (1:1000 diluted). Predicted band size: 24kDa. Observed band size: 24kDa.Applications for Geminin Antibody (S08-1F8)
Application
Recommended Usage
Western Blot
1/1000
Formulation, Preparation, and Storage
Purification
Affinity purified
Formulation
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA
Preservative
0.01% Sodium Azide
Concentration
0.3 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: Geminin
Geminin prevents DNA replication by blocking the MCM complex incorporation into prereplication complex (pre-RC). It is absent during the G1 phase and accumulates during the S, G2, and M phases of mitosis. Geminin is then degraded during the metaphase-anaphase trasitio,n allowing replication to occur during subsequent cycles.
Geminin antibodies are useful tools for a variety of research including developmental embryology, stem cell differentiation, neuroscience, and DNA replication studies.
Alternate Names
Gem, geminin, geminin, DNA replication inhibitor, RP3-369A17.3
Gene Symbol
GMNN
Additional Geminin Products
Product Documents for Geminin Antibody (S08-1F8)
Product Specific Notices for Geminin Antibody (S08-1F8)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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