Geminin Antibody
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-56766
Key Product Details
Species Reactivity
Human
Applications
Immunocytochemistry/ Immunofluorescence
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: GRENELSAGLSKRKHRNDHLTSTTSSPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWK
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Scientific Data Images for Geminin Antibody
![Immunocytochemistry/ Immunofluorescence: Geminin Antibody [NBP2-56766]](https://resources.bio-techne.com/images/products/Geminin-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-56766-img0001.jpg "Immunocytochemistry/ Immunofluorescence: Geminin Antibody [NBP2-56766]")
Immunocytochemistry/ Immunofluorescence: Geminin Antibody [NBP2-56766]
Immunocytochemistry/Immunofluorescence: Geminin Antibody [NBP2-56766] - Staining of human cell line U-2 OS shows localization to nucleus.Applications for Geminin Antibody
Application
Recommended Usage
Immunocytochemistry/ Immunofluorescence
0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Formulation, Preparation, and Storage
Purification
Affinity purified
Formulation
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: Geminin
Geminin prevents DNA replication by blocking the MCM complex incorporation into prereplication complex (pre-RC). It is absent during the G1 phase and accumulates during the S, G2, and M phases of mitosis. Geminin is then degraded during the metaphase-anaphase trasitio,n allowing replication to occur during subsequent cycles.
Geminin antibodies are useful tools for a variety of research including developmental embryology, stem cell differentiation, neuroscience, and DNA replication studies.
Alternate Names
Gem, geminin, geminin, DNA replication inhibitor, RP3-369A17.3
Gene Symbol
GMNN
Additional Geminin Products
Product Documents for Geminin Antibody
Product Specific Notices for Geminin Antibody
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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