GFR alpha-3/GDNF R alpha-3 Antibody (118) [Janelia Fluor® 635]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-89342JF635

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA

Label

Janelia Fluor 635

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 118

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all GFR alpha-3/GDNF R alpha-3 Antibodies »

Product Summary for GFR alpha-3/GDNF R alpha-3 Antibody (118) [Janelia Fluor® 635]

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Human GFR alpha-3/GDNF R alpha-3 (Accession#: NP_001487.2; Met 1-Trp 382).

Specificity

No cross-reactivity in ELISA with: Rat GFRA1Human GFRa2

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Applications for GFR alpha-3/GDNF R alpha-3 Antibody (118) [Janelia Fluor® 635]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: GFR alpha-3/GDNF R alpha-3

Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN), play key roles in the control of vertebrate neuronal survival and differentiation. A new member of the GDNF family was recently identified and designated persephin. Physiological responses to these neurotrophic factors require two receptor subunits, the novel glycosylphosphatidylinositol linked protein GFRalpha and Ret receptor tyrosine kinase GFRbeta. Following the identification of GFRalpha-1 and 2, another receptor in the GFR family was identified in human and mouse and designated GFRalpha-3. GFRalpha-3 binds persephin. Thus, persephin, GFRalpha-3, and Ret PTK form a complex to transmit the persephin signal and to mediate persephin function.

Long Name

Glial Cell line-derived Neurotrophic Factor Receptor alpha 3

Alternate Names

GDNF R alpha-3, GFR alpha3, GFRa-3, GFRA3

Gene Symbol

GFRA3

Additional GFR alpha-3/GDNF R alpha-3 Products

Product Documents for GFR alpha-3/GDNF R alpha-3 Antibody (118) [Janelia Fluor® 635]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for GFR alpha-3/GDNF R alpha-3 Antibody (118) [Janelia Fluor® 635]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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