GIPC2 Antibody (1G10) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-22552

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 1G10

Format

BSA Free

Concentration

1 mg/ml

View all GIPC2 Antibodies »

Product Summary for GIPC2 Antibody (1G10) - BSA Free

Immunogen

Recombinant human GIPC2 (1-315aa) purified from E. coli

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for GIPC2 Antibody (1G10) - BSA Free

Western Blot: GIPC2 Antibody (1G10)BSA Free [NBP2-22552]

Western Blot: GIPC2 Antibody (1G10)BSA Free [NBP2-22552]

Western Blot: GIPC2 Antibody (1G10) [NBP2-22552] - The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human GIPC antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.The cross-reacting of anti-human GIPC (AT1G10) were analyzed by using recombinant protein(20ng) of GIPC1 and GIPC2.

Applications for GIPC2 Antibody (1G10) - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS (pH 7.4), 10% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GIPC2

GIPC, GAIP interacting protein at the C terminus, is a PDZ domain containing protein that interacts with RGS-GAIP. GIPC was also identified as TIP-2, a protein that interacts with the viral oncoprotein TAX, which transactivates viral and cellular promoters through interactions with various transcription factors. GIPC specifically localizes to clusters of vesicles near the plasma membrane and participates in G protein-coupled signaling pathway involved in regulating clathrin-coated vesicular trafficking. GIPC also associates with membrane bound semaphorin F (M-SemF), which is involved in neuronal axon growth, and it appears to regulate the subcellular distribution of M-SemF in the brain.

Alternate Names

FLJ20075, GIPC PDZ domain containing family, member 2, PDZ domain protein GIPC2, PDZ domain-containing protein GIPC2, semaF cytoplasmic domain associated protein 2, semaphorin cytoplasmic domain associated protein 2, SEMCAP2, SEMCAP-2

Gene Symbol

GIPC2

UniProt

NP_060125.4 (Human)

Additional GIPC2 Products

Product Documents for GIPC2 Antibody (1G10) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GIPC2 Antibody (1G10) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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