Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # OTI9G8

Concentration

1 mg/ml

View all GITR/TNFRSF18 Antibodies »

Product Specifications

Immunogen

Human recombinant protein fragment corresponding to amino acids 26-162 of human TNFRSF18(NP_004186) produced in E.coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Theoretical MW

23.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for GITR/TNFRSF18 Antibody (OTI9G8)

Western Blot: GITR/TNFRSF18 Antibody (OTI9G8) [NBP2-46156]

Western Blot: GITR/TNFRSF18 Antibody (OTI9G8) [NBP2-46156]

Western Blot: GITR/TNFRSF18 Antibody (9G8) [NBP2-46156] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TNFRSF18.
Immunohistochemistry: GITR/TNFRSF18 Antibody (OTI9G8) [NBP2-46156]

Immunohistochemistry: GITR/TNFRSF18 Antibody (OTI9G8) [NBP2-46156]

Immunohistochemistry: GITR/TNFRSF18 Antibody (9G8) [NBP2-46156] - Analysis of Human lymphoma tissue.
Immunohistochemistry: GITR/TNFRSF18 Antibody (OTI9G8) [NBP2-46156]

Immunohistochemistry: GITR/TNFRSF18 Antibody (OTI9G8) [NBP2-46156]

Immunohistochemistry: GITR/TNFRSF18 Antibody (9G8) [NBP2-46156] - Analysis of Adenocarcinoma of Human colon tissue.

Applications for GITR/TNFRSF18 Antibody (OTI9G8)

Application
Recommended Usage

Immunohistochemistry

1:150

Western Blot

1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: GITR/TNFRSF18

GITR is encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]

Long Name

Glucocorticoid Induced TNF Receptor Family Related Gene

Alternate Names

AITR, CD357, TNFRSF18

Gene Symbol

TNFRSF18

Additional GITR/TNFRSF18 Products

Product Documents for GITR/TNFRSF18 Antibody (OTI9G8)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for GITR/TNFRSF18 Antibody (OTI9G8)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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