Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # T9P4G4*D7

Format

BSA Free

Concentration

0.8 mg/ml

View all GITR/TNFRSF18 Antibodies »

Product Summary for GITR/TNFRSF18 Antibody (T9P4G4*D7) - BSA Free

Immunogen

Peptide Sequence - TEDARSCQFP

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Scientific Data Images for GITR/TNFRSF18 Antibody (T9P4G4*D7) - BSA Free

Western Blot: GITR/TNFRSF18 Antibody (T9P4G4/D7) [NBP2-50337]
Immunohistochemistry: GITR/TNFRSF18 Antibody (T9P4G4/D7) [NBP2-50337]
Immunohistochemistry: GITR/TNFRSF18 Antibody (T9P4G4*D7) - BSA Free [NBP2-50337]

Immunohistochemistry: GITR/TNFRSF18 Antibody (T9P4G4*D7) - BSA Free [NBP2-50337]

Immunohistochemistry: GITR/TNFRSF18 Antibody (T9P4G4/D7) [NBP2-50337] - Staining of GITR in a normal lymph node tissue cross section. Positive cytoplasmic/membranous immunostaining is observed in agreement with the literature.

Applications for GITR/TNFRSF18 Antibody (T9P4G4*D7) - BSA Free

Application
Recommended Usage

ELISA

1:100 - 1:2000

Immunohistochemistry

1:10 - 1:500

Western Blot

1:100 - 1:2000
Application Notes
Positive control(s): ELISA - peptide immunogen; IHC - formalin-fixed, paraffin-embedded breast cancer sections; WB - Jurkat whole cell lysates.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

0.8 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GITR/TNFRSF18

GITR is encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]

Long Name

Glucocorticoid Induced TNF Receptor Family Related Gene

Alternate Names

AITR, CD357, TNFRSF18

Gene Symbol

TNFRSF18

Additional GITR/TNFRSF18 Products

Product Documents for GITR/TNFRSF18 Antibody (T9P4G4*D7) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for GITR/TNFRSF18 Antibody (T9P4G4*D7) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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