GKAP/DLGAP1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76911

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all GKAP/DLGAP1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 18 amino acid synthetic peptide from near the center of human SAPAP1. The immunogen is located within amino acids 640 - 690 of SAPAP1. Amino Acid Squence: VDDAEEPDKTGENKAPSK

Specificity

At least three isoforms of SAPAP1 are known to exist. This SAPAP1 antibody will not cross-react with other SAPAP proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GKAP/DLGAP1 Antibody - BSA Free

Western Blot: GKAP/DLGAP1 AntibodyBSA Free [NBP1-76911]

Western Blot: GKAP/DLGAP1 AntibodyBSA Free [NBP1-76911]

Western Blot: GKAP/DLGAP1 Antibody [NBP1-76911] - Analysis in rat brain tissue lysate with antibody at (A) 0.5 and (B) 1 ug/mL.
Immunocytochemistry/ Immunofluorescence: GKAP/DLGAP1 Antibody - BSA Free [NBP1-76911]

Immunocytochemistry/ Immunofluorescence: GKAP/DLGAP1 Antibody - BSA Free [NBP1-76911]

Immunocytochemistry/Immunofluorescence: GKAP/DLGAP1 Antibody [NBP1-76911] - Human Brain cells
Immunohistochemistry-Paraffin: GKAP/DLGAP1 Antibody - BSA Free [NBP1-76911]

Immunohistochemistry-Paraffin: GKAP/DLGAP1 Antibody - BSA Free [NBP1-76911]

Immunohistochemistry-Paraffin: GKAP/DLGAP1 Antibody [NBP1-76911] - Human brain with DLGAP1 antibody at 5 ug/ml.
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Applications for GKAP/DLGAP1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

0.5-1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GKAP/DLGAP1

SAP90/PSD-95-associated protein 1 (SAPAP1, also known as DLGAP1 or GKAP) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP1 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP1 mRNA is targeted to cell bodies in a similar manner to SAPAP2 and -4, whereas SAPAP3 mRNA is detected mainly in cell bodies. SAPAP1 protein however, is targeted to the synapse and is not reliant on the synaptic localization of PSD-95 or the synaptic scaffolding molecule (S-SCAM). At least three isoforms of SAPAP1 are known to exist. This SAPAP1 antibody will not cross-react with other SAPAP proteins.

Long Name

Guanylate Kinase-associated Protein

Alternate Names

DAP1, DLGAP1, SAPAP1

Gene Symbol

DLGAP1

UniProt

NP_004737 (Human)

Additional GKAP/DLGAP1 Products

Product Documents for GKAP/DLGAP1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GKAP/DLGAP1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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