GLP-2R Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS1312

Novus Biologicals, part of Bio-Techne
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NLS1312
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Key Product Details

Species Reactivity

Validated:

Human, Guinea Pig, Monkey

Predicted:

Primate (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all GLP-2R Antibodies »

Product Specifications

Immunogen

Synthetic 18 amino acid peptide from N-terminal extracellular domain of human GLP-2R.

Epitope

N-Terminus extracellular domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Marmoset (100%), Gibbon (94%), Bovine (89%), Canine (89%), Porcine (89%), Bat (83%), Rabbit (83%).

Localization

Secreted

Specificity

Human GLP2R. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for GLP-2R Antibody - BSA Free

Immunohistochemistry-Paraffin: GLP-2R Antibody - BSA Free [NLS1312]

Immunohistochemistry-Paraffin: GLP-2R Antibody - BSA Free [NLS1312]

Immunohistochemistry-Paraffin: GLP-2R Antibody [NLS1312] - Analysis of anti-GLP2R antibody with human small intestine, neuroendocrine cells.
GLP-2R Antibody - BSA Free

Immunohistochemistry-Paraffin: GLP-2R Antibody - BSA Free [NLS1312] -

Immunohistochemistry-Paraffin: GLP-2R Antibody - BSA Free [NLS1312] - Immunohistochemistry of formalin-fixed, paraffin-embedded human small intestine, neuroendocrine cells tissue after heat-induced antigen retrieval.

Applications for GLP-2R Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry

1:10 - 1:500

Immunofluorescence

1:10 - 1:500

Immunohistochemistry-Paraffin

10 - 20 ug/ml

Immunoprecipitation

1:10 - 1:500

Western Blot

1:100 - 1:2000
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: GLP-2R

GLP2R, a Glucagon Receptor, is closely related to the Glucagon Receptor and to the GLP1 Receptor. The glucagon-like peptides (GLP-1 and GLP-2) are proglucagon-derived peptides cosecreted from gut endocrine cells in response to nutrient ingestion. The actions of GLP-2 are mediated by the GLP-2 receptor expressed on subsets of enteric nerves and enteroendocrine cells in the stomach and small and large intestine. Activation of GLP2R signaling promotes expansion of the mucosal epithelium indirectly via activation of growth and anti-apoptotic pathways. GLP2R, through its ligand glucagon-like peptide 2 (GLP2), has been shown to prevent intestinal hypoplasia resulting from total parenteral nutrition. GLP2R has been reported primarily in the gastrointestinal tract, including intestine and stomach. In rats, GLPR2 has been shown in brain and lung. An EST has been isolated from a lung cancer library.

Long Name

Glucagon-like Peptide 2 Receptor

Alternate Names

GLP2R

Entrez Gene IDs

9340 (Human)

Gene Symbol

GLP2R

Additional GLP-2R Products

Product Documents for GLP-2R Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for GLP-2R Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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