GLP/EHMT1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-17670

Novus Biologicals, part of Bio-Techne
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NBP3-17670-100ul
NBP3-17670-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (90%), Rat (92%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GLP/EHMT1 Antibodies »

Product Summary for GLP/EHMT1 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DCVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWSALQMSKALQDSAPDRPSPVERIVSRDIARGYERIPIPCVNAVDSEPCPSNYKYV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GLP/EHMT1 Antibody

Immunohistochemistry-Paraffin: GLP/EHMT1 Antibody [NBP3-17670]

Immunohistochemistry-Paraffin: GLP/EHMT1 Antibody [NBP3-17670]

Immunohistochemistry-Paraffin: GLP/EHMT1 Antibody [NBP3-17670] - Staining of human testis shows strong nuclear positivity in cells in seminiferous ducts.

Applications for GLP/EHMT1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GLP/EHMT1

Euchromatic histone-lysine N-methyltransferase 1 (EHMT1) is a histone methyltransferase that catalyzes the methylation of lysine-9 of histone H3 (H3-K9). H3-K9 histone methylation is restricted to euchromatin and functions to epigenetically silence gene transcription. Loss of function mutations in EHMT1 cause the 9q34 subtelomeric deletion syndrome, a syndrome characterized by severe mental retardation, hypotonia, brachy(micro)cephaly, heart defects, and distinct facial anomalies. Alternate names for EHMT1 include histone H3-K9 methyltransferase 5, H3-K9-HMTase5, eu-HMTase, G9a-like protein 1, GLP1, lysine N-methyltransferase 1D, EUHMTASE1, KMT1D, and KIAA1876.

Long Name

G9a-like Protein 1/Euchromatic Histone-Lysine N-Methyltransferase 1

Alternate Names

DEL9q34, EHMT1, Eu-HMTase1, KMT1D, Lysine N-methyltransferase 1D

Gene Symbol

EHMT1

Additional GLP/EHMT1 Products

Product Documents for GLP/EHMT1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for GLP/EHMT1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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