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Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-68917

Novus Biologicals, part of Bio-Techne
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NBP1-68917

Key Product Details

Species Reactivity

Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Synthetic peptides corresponding to Gns (glucosamine (N-acetyl)-6-sulfatase) The peptide sequence was selected from the C terminal of Gns. Peptide sequence YIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIKPNQTSKMLV. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

58 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody

Western Blot: Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody [NBP1-68917]

Western Blot: Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody [NBP1-68917]

Western Blot: GNS Antibody [NBP1-68917] - Titration: 0.2-1 ug/ml, Positive Control: Rat Heart.

Applications for Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Glucosamine (N-acetyl)-6-Sulfatase/GNS

GNS is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparin sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder ucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.

Alternate Names

Glucosamine6Sulfatase, GNS

Gene Symbol

GNS

UniProt

Additional Glucosamine (N-acetyl)-6-Sulfatase/GNS Products

Product Documents for Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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