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Glucosylceramidase/GBA Antibody (4H4)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-26559

Recombinant monoclonal antibody expressed in HEK293F cells
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-26559-100ul
NBP3-26559-50ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 4H4

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for Glucosylceramidase/GBA Antibody (4H4)

Immunogen

A synthesized peptide derived from Human Glucosylceramidase/GBA [UniProt P04062]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Glucosylceramidase/GBA Antibody (4H4)

Glucosylceramidase/GBA Antibody (4H4)

Western Blot: Glucosylceramidase/GBA Antibody (4H4) [NBP3-26559] -

Western Blot: Glucosylceramidase/GBA Antibody (4H4) [NBP3-26559] - Positive Western Blot detected in: Hela whole cell lysate, MCF-7 whole cell lysate, 293T whole cell lysate, U87 whole cell lysate.
All lanes: Glucosylceramidase/GBA Antibody at 1: 2000
Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution.
Predicted band size: 60, 58, 55, 51, 30 kDa
Observed band size: 60 kDa

Applications for Glucosylceramidase/GBA Antibody (4H4)

Application
Recommended Usage

Western Blot

1:500-1:5000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl and 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -70C. Avoid freeze-thaw cycles.

Background: Glucosylceramidase/GBA

GBA encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants encoding the same protein.

Alternate Names

Alglucerase, GBA, GBA1, Imiglucerase

Gene Symbol

GBA1

Additional Glucosylceramidase/GBA Products

Product Documents for Glucosylceramidase/GBA Antibody (4H4)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Glucosylceramidase/GBA Antibody (4H4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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