GluR2/3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB300-302

Novus Biologicals, part of Bio-Techne
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NB300-302
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Key Product Details

Species Reactivity

Validated:

Rat

Predicted:

Chicken (100%), Human (100%), Mouse (100%), Zebrafish (100%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all GluR2/3 Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH. Accession # P19491

Localization

Cell Membrane; multi-pass membrane protein.

Specificity

Specific for endogenous levels of the ~100 kDa GluR2/3 protein.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

100 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for GluR2/3 Antibody

Western Blot: GluR2/3 Antibody [NB300-302]

Western Blot: GluR2/3 Antibody [NB300-302]

Western Blot: GluR2/3 Antibody [NB300-302] - Analysis of GluR2/3 in rat brain hippocampus lysate using NB300-302 at 1:1000.

Applications for GluR2/3 Antibody

Application
Recommended Usage

Western Blot

1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: GluR2/3

The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by a-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct Glutamate Receptor Subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain. The GluR2 subunit is widely expressed throughout the nervous system where it is thought to play key roles in synaptic plasticity and learning and memory.

Long Name

Glutamate Receptor 2/3

Alternate Names

AMPA 2, glutamate receptor, ionotropic, AMPA 2

Entrez Gene IDs

2891 (Human); 14800 (Mouse); 29627 (Rat)

Gene Symbol

GRIA2

UniProt

P19491 (Rat)

Additional GluR2/3 Products

Product Documents for GluR2/3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for GluR2/3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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