GluR2 Antibody (7A7A3) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-61775

Novus Biologicals, part of Bio-Techne
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NBP2-61775
NBP2-61775-0.025ml
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Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 7A7A3

Format

BSA Free

Concentration

1 mg/ml

View all GluR2 Antibodies »

Product Summary for GluR2 Antibody (7A7A3) - BSA Free

Immunogen

Purified recombinant fragment of human GluR2 (AA: 35-175) expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Theoretical MW

99 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for GluR2 Antibody (7A7A3) - BSA Free

Western Blot: GluR2 Antibody (7A7A3)BSA Free [NBP2-61775]

Western Blot: GluR2 Antibody (7A7A3)BSA Free [NBP2-61775]

Western Blot: GluR2 Antibody (7A7A3) [NBP2-61775] - Analysis using GRIA2 mAb against human GRIA2 (AA: 35-175) recombinant protein. (Expected MW is 41.9 kDa)
Immunohistochemistry-Paraffin: GluR2 Antibody (7A7A3) - BSA Free [NBP2-61775]

Immunohistochemistry-Paraffin: GluR2 Antibody (7A7A3) - BSA Free [NBP2-61775]

Immunohistochemistry-Paraffin: GluR2 Antibody (7A7A3) [NBP2-61775] - Analysis of rectum cancer tissues using GRIA2 mouse mAb with DAB staining.
Flow Cytometry: GluR2 Antibody (7A7A3) - BSA Free [NBP2-61775]

Flow Cytometry: GluR2 Antibody (7A7A3) - BSA Free [NBP2-61775]

Flow Cytometry: GluR2 Antibody (7A7A3) [NBP2-61775] - Analysis of SK-N-SH cells using GRIA2 mouse mAb (green) and negative control (red).
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Applications for GluR2 Antibody (7A7A3) - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Flow Cytometry

1:10-1:1000

Immunohistochemistry

1:200-1:1000

Immunohistochemistry-Paraffin

1:200 - 1:1000

Western Blot

1:100-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GluR2

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.

Long Name

Glutamate Receptor 2

Alternate Names

AMPA2, GluA2, GluR-K2, GLURB, GRIA2, HBGR2

Gene Symbol

GRIA2

Additional GluR2 Products

Product Documents for GluR2 Antibody (7A7A3) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for GluR2 Antibody (7A7A3) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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