GluR5/GRIK1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24871

Novus Biologicals, part of Bio-Techne
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NBP3-24871
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (90%), Rat (90%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GluR5/GRIK1 Antibodies »

Product Specifications

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein GluR5/GRIK1 using the following amino acid sequence: TEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTDSNKDKSSNITDSLANRTL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GluR5/GRIK1 Antibody

GluR5/GRIK1 Antibody Immunocytochemistry/Immunofluorescence: GluR5/GRIK1 Antibody [NBP3-24871]

Immunocytochemistry/Immunofluorescence: GluR5/GRIK1 Antibody [NBP3-24871]

Staining of human cell line HeLa shows localization to plasma membrane.

Applications for GluR5/GRIK1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GluR5/GRIK1

Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamategated, caution-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brain stem whereas the four epsilon subunits display limited distribution.

Long Name

Glutamate Receptor 5

Alternate Names

EAA3, EEA3, GluK1, GRIK1

Gene Symbol

GRIK1

Additional GluR5/GRIK1 Products

Product Documents for GluR5/GRIK1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GluR5/GRIK1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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