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Glutathione Peroxidase 5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-41832

Novus Biologicals, part of Bio-Techne
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NBP3-41832

Key Product Details

Species Reactivity

Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.74 mg/ml

Product Specifications

Immunogen

Immunized with recombinant Rat Glutathione Peroxidase 5 (Uniprot#: P30710; Thr22-Ile221 (Uniprot#: P30710)

Clonality

Polyclonal

Host

Rabbit

Applications for Glutathione Peroxidase 5 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

5-20ug/mL

Immunohistochemistry

5-20ug/mL

Western Blot

0.5-2ug/mL

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS, pH7.4, 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

0.74 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Glutathione Peroxidase 5

Glutathione peroxidase (GPX)/glutathione reductase is part of the hydrogen peroxide scavenging system found within the epididymis in the mammalian male reproductive tract. GPX5 expression is epididymis-specific and the transcript is unique from other GPXs because it contains a deletion resulting in an mRNA that does not contain a selenocysteine (UGA) codon (an unusual amino acid present in other GPXs). This deletion also renders the mRNA incapable of encoding an active GPX isoenzyme. For this reason, GPX5 is selenium-independent and has very little activity towards hydrogen peroxide or organic hydroperoxides. GPX5, which is bound to the acrosome of sperm, may act to protect sperm from premature acrosome reaction in the epididymis. [provided by RefSeq]

Alternate Names

EC 1.11.1, EC 1.11.1.9, EGLP, epididymal androgen-related protein, epididymal secretory glutathione peroxidase, Epididymis-specific glutathione peroxidase-like protein, Glutathione peroxidase 5, glutathione peroxidase 5 (epididymal androgen-related protein), GPx-5, GSHPx-5

Gene Symbol

GPX5

Additional Glutathione Peroxidase 5 Products

Product Documents for Glutathione Peroxidase 5 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Glutathione Peroxidase 5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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