Glutathione Reductase Antibody (S08-2E4)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15033

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-15033-100ul
NBP3-15033-25ul
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S08-2E4

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Glutathione Reductase Antibodies »

Product Specifications

Immunogen

A synthetic peptide of human Glutathione Reductase (Uniprot#: P00390)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

51 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Glutathione Reductase Antibody (S08-2E4)

Western Blot: Glutathione Reductase Antibody (S08-2E4) [NBP3-15033]

Western Blot: Glutathione Reductase Antibody (S08-2E4) [NBP3-15033]

Western Blot: Glutathione Reductase Antibody (S08-2E4) [NBP3-15033] - Western blot detection of Glutathione Reductase in Hela, Jurkat cell lysates using Glutathione Reductase Rabbit mAb (1:500 diluted). Predicted band size: 56kDa. Observed band size: 51kDa.

Applications for Glutathione Reductase Antibody (S08-2E4)

Application
Recommended Usage

Western Blot

1/2000-1/10000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Glutathione Reductase

Glutathione reductase (GR) is a member of pyridine nucleotide-disulfideoxidoreductases, which includes the closely related enzymes thioredoxin reductase, lipoamide dehydrogenase, trypanothione reductase and mercuric ion reductase. GR is a cytoplasmic flavoenzyme widely distributed in aerobic organisms. The dimeric protein is composed of two identical subunits, each containing 1 FAD and 1 redox-active disulfide/dithiol as components of the catalytic apparatus. It plays a role in maintaining glutathione(GSH) in its reduced form by catalyzing the reduction of glutathione disulfide (GSSG): GSSG + NADPH + H+ ->2GSH + NADP+. In mosteukaryotic cells, GR maintains the ratio of [GSH]/[GSSG], and participates in several vital functions such as the detoxification of reactive oxygen species as well as protein and DNA biosynthesis.

Alternate Names

GLUR, GRase, GRD1, GSR, HEL-752

Gene Symbol

GSR

Additional Glutathione Reductase Products

Product Documents for Glutathione Reductase Antibody (S08-2E4)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Glutathione Reductase Antibody (S08-2E4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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