Glutathione S-Transferase pi 1/GSTP1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76857

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (93%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Glutathione S-Transferase pi 1/GSTP1 Antibodies »

Product Summary for Glutathione S-Transferase pi 1/GSTP1 Antibody - BSA Free

Immunogen

Antibody was raised against a 14 amino acid synthetic peptide from near the center of human GSTP1. The immunogen is located within amino acids 90 - 140 of GSTP1. Amino Acid Squence: YTNYEAGKDDYVKA

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Goat (86%), Pig (85%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Glutathione S-Transferase pi 1/GSTP1 Antibody - BSA Free

Western Blot: Glutathione S-Transferase pi 1/GSTP1 AntibodyBSA Free [NBP1-76857]

Western Blot: Glutathione S-Transferase pi 1/GSTP1 AntibodyBSA Free [NBP1-76857]

Western Blot: Glutathione S-Transferase pi 1/GSTP1 Antibody [NBP1-76857] - Jurkat cell lysate with GSTP1 antibody at (A) 0.5 and (B) 1 ug/mL.
Immunocytochemistry/ Immunofluorescence: Glutathione S-Transferase pi 1/GSTP1 Antibody - BSA Free [NBP1-76857]

Immunocytochemistry/ Immunofluorescence: Glutathione S-Transferase pi 1/GSTP1 Antibody - BSA Free [NBP1-76857]

Immunocytochemistry/Immunofluorescence: Glutathione S-Transferase pi 1/GSTP1 Antibody [NBP1-76857] - Immunofluorescence of GSTP1 in Human Lung cells with GSTP1 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: Glutathione S-Transferase pi 1/GSTP1 Antibody - BSA Free [NBP1-76857]

Immunohistochemistry-Paraffin: Glutathione S-Transferase pi 1/GSTP1 Antibody - BSA Free [NBP1-76857]

Immunohistochemistry-Paraffin: Glutathione S-Transferase pi 1/GSTP1 Antibody [NBP1-76857] - Human lung tissue using GSTP1 antibody at 2.5 ug/ml.

Applications for Glutathione S-Transferase pi 1/GSTP1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

0.5-1 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Glutathione S-Transferase pi 1/GSTP1

Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism (i.e., the metabolism of environmental mutagens and carcinogens) and may play a role in susceptibility to cancer. More recent experiments have suggested that differential expression of GSTP1 also contributes to the sensitivity of xenobiotics in the substantia nigra and may influence the pathogenesis of reactive oxygen species-induced neurological disorders such as Parkinson's disease. CpG island hypermethylation of the GSTP1 promoter leading to the silencing of the GSTP1 gene has also been linked to cancer.

Alternate Names

DFN7, FAEES3, Glutathione STransferase pi 1, GSTP1

Gene Symbol

GSTP1

UniProt

NP_000843 (Human)

Additional Glutathione S-Transferase pi 1/GSTP1 Products

Product Documents for Glutathione S-Transferase pi 1/GSTP1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Glutathione S-Transferase pi 1/GSTP1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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