GMPS Antibody (1D10)

Novus Biologicals, part of Bio-Techne | Catalog # H00008833-M01

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Product Datasheet / COA / SDS

Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG₁ kappa Clone # 1D10

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GMPS Antibodies »

Product Specifications

Immunogen

GMPS (NP_003866, 108 a.a. ~ 215 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. QMMNKVFGGTVHKKSVREDGVFNISVDNTCSLFRGLQKEEVVLLTHGDSVDKVADGFKVVARSGNIVAGIANESKKLYGAQFHPEVGLTENGKVILKNFLYDIAGCSG

Specificity

GMPS - guanine monphosphate synthetase

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁ kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for GMPS Antibody (1D10)

Immunohistochemistry-Paraffin: GMPS Antibody (1D10) [H00008833-M01]

Immunohistochemistry-Paraffin: GMPS Antibody (1D10) [H00008833-M01] - Analysis of monoclonal antibody to GMPS on formalin-fixed paraffin-embedded human small Intestine. Antibody concentration 1.5 ug/ml.

Immunohistochemistry-Paraffin: GMPS Antibody (1D10) [H00008833-M01]

Immunohistochemistry-Paraffin: GMPS Antibody (1D10) [H00008833-M01] - Immunoperoxidase of monoclonal antibody to GMPS ( Cat # H00008833-M01 ) on formalin-fixed paraffin-embedded human stomach. [antibody concentration 3 ug/ml]

Sandwich ELISA: GMPS Antibody (1D10) [H00008833-M01] - Detection limit for recombinant GST tagged GMPS is approximately 0.1ng/ml as a capture antibody.

Applications for GMPS Antibody (1D10)

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Sandwich ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Antibody reactivity against recombinant protein for WB. It has been used for IHC-P and ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: GMPS

In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.

Alternate Names

EC 6.3.5.2, Glutamine amidotransferase, GMP synthase, GMP synthase [glutamine-hydrolyzing], GMP synthetase, guanine monphosphate synthetase, guanosine 5'-monophosphate synthase, MLL/GMPS fusion protein

Entrez Gene IDs

8833 (Human)

Gene Symbol

GMPS

OMIM

600358 (Human)

UniProt

NP_003866 (Human)

Additional GMPS Products

Product Documents for GMPS Antibody (1D10)

Product Datasheets

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COA

SDS

Product Specific Notices for GMPS Antibody (1D10)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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