GNAQ Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-31985

Novus Biologicals, part of Bio-Techne
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NBP1-31985
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%), Canine (100%), Chicken (98%), Porcine (100%), Rhesus Macaque (100%), Xenopus (96%), Zebrafish (93%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GNAQ Antibodies »

Product Summary for GNAQ Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human GNAQ. The exact sequence is proprietary.

Reactivity Notes

Xenopus laevis (96%).

Localization

N/A

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

42 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for GNAQ Antibody

Western Blot: GNAQ Antibody [NBP1-31985]

Western Blot: GNAQ Antibody [NBP1-31985]

Western Blot: GNAQ Antibody [NBP1-31985] - A. 30 ug 293T whole cell extract B. 30 ug whole cell extract of 3xFlag-human GNAQ-transfected 293T cells 10 % SDS-PAGE GNAQ antibody dilution: 1:1000
Immunohistochemistry-Paraffin: GNAQ Antibody [NBP1-31985]

Immunohistochemistry-Paraffin: GNAQ Antibody [NBP1-31985]

Immunohistochemistry-Paraffin: GNAQ Antibody [NBP1-31985] - Paraffin-embedded mouse ovary. GNAQ antibody dilution: 1:500.
Western Blot: GNAQ Antibody [NBP1-31985]

Western Blot: GNAQ Antibody [NBP1-31985]

Western Blot: GNAQ Antibody [NBP1-31985] - Whole cell extract (30 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with GNAQ antibody diluted at 1:500.
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Applications for GNAQ Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: GNAQ

Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit. G-alpha-q is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta (MIM 600230).[supplied by OMIM]

Alternate Names

GAQG-ALPHA-q, guanine nucleotide binding protein (G protein), q polypeptide, Guanine nucleotide-binding protein alpha-q, guanine nucleotide-binding protein G(q) subunit alpha

Gene Symbol

GNAQ

Additional GNAQ Products

Product Documents for GNAQ Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for GNAQ Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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