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GPR74/NPFFR2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS3304

Novus Biologicals, part of Bio-Techne
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NLS3304

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Primate (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

Product Specifications

Immunogen

Synthetic 18 amino acid peptide from C-terminus of human GPR74/NPFFR2.

Epitope

C-Terminus

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (94%), Marmoset (89%).

Specificity

Human NPFFR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for GPR74/NPFFR2 Antibody - BSA Free

Immunohistochemistry-Paraffin: GPR74/NPFFR2 Antibody - BSA Free [NLS3304]

Immunohistochemistry-Paraffin: GPR74/NPFFR2 Antibody - BSA Free [NLS3304]

Immunohistochemistry-Paraffin: GPR74/NPFFR2 Antibody [NLS3304] - Analysis of anti-NPFF2 / NPFFR2 antibody with human colon at dilution 4-7 ug/ml.
Immunohistochemistry-Paraffin: GPR74/NPFFR2 Antibody - BSA Free [NLS3304]

Immunohistochemistry-Paraffin: GPR74/NPFFR2 Antibody - BSA Free [NLS3304]

Immunohistochemistry-Paraffin: GPR74/NPFFR2 Antibody [NLS3304] - Analysis of anti-NPFF2 / NPFFR2 antibody with human testis.

Applications for GPR74/NPFFR2 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

4-7 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: GPR74/NPFFR2

The Neuropeptide FF 2 Receptor (NPFF2/HLWAR77/NPGPR) is a Neuropeptide Receptor GPCR. This receptor has high affinity for NPAF and NPFF, and is also weakly activated by FMRF-amide (Phe-Met-Arg-Phe-amide) and a variety of related peptides. The receptor is expressed in brain regions associated with opiate activity, consistent with the pain-modulating activity of these peptides, and in adipose tissue, suggesting other physiological and pathophysiological activities for FMRF-amide neuropeptides (Elshourbagy et al, 2000). Two isoforms are produced by alternative splicing. NPFF2 receptor has been reported to be expressed in various tissues, including brain, heart, intestine, placenta, prostate, spleen, adipose, spinal cord, colon, kidney, liver, lung, ovary, testis, pancreas, and thymus. ESTs have been isolated from fetal and placenta libraries.

Long Name

G Protein-coupled Receptor 74

Alternate Names

NPFF2, NPFFR2, NPGPR

Entrez Gene IDs

10886 (Human)

Gene Symbol

NPFFR2

UniProt

Additional GPR74/NPFFR2 Products

Product Documents for GPR74/NPFFR2 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GPR74/NPFFR2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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