GPS2 Antibody (3C4)

Novus Biologicals, part of Bio-Techne | Catalog # H00002874-M01

Novus Biologicals, part of Bio-Techne
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H00002874-M01
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 3C4

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GPS2 Antibodies »

Product Specifications

Immunogen

GPS2 (AAH13652, 228 a.a. ~ 327 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. QPYAVHGHFQPTQTGFLQPGGALSLQKQMEHANQQTGFSDSSSLRPMHPQALHPAPGLLASPQLPVQMQPAGKSGFAATSQPGPRLPFIQHSQNPRFYHK

Specificity

GPS2 - G protein pathway suppressor 2

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for GPS2 Antibody (3C4)

Western Blot: GPS2 Antibody (3C4) [H00002874-M01]

Western Blot: GPS2 Antibody (3C4) [H00002874-M01]

Western Blot: GPS2 Antibody (3C4) [H00002874-M01] - Analysis of GPS2 expression in transfected 293T cell line by GPS2 monoclonal antibody (M01), clone 3C4.Lane 1: GPS2 transfected lysate (Predicted MW: 36.7 KDa).Lane 2: Non-transfected lysate.
ELISA: GPS2 Antibody (3C4) [H00002874-M01]

ELISA: GPS2 Antibody (3C4) [H00002874-M01]

ELISA: GPS2 Antibody (3C4) [H00002874-M01] - Detection limit for recombinant GST tagged GPS2 is approximately 0.3ng/ml as a capture antibody.

Applications for GPS2 Antibody (3C4)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: GPS2

This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.

Alternate Names

AMF-1, G protein pathway suppressor 2, GPS-2, MGC104294, MGC119287, MGC119288, MGC119289

Entrez Gene IDs

2874 (Human)

Gene Symbol

GPS2

OMIM

601935 (Human)

UniProt

AAH13652 (Human)

Additional GPS2 Products

Product Documents for GPS2 Antibody (3C4)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for GPS2 Antibody (3C4)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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