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GPS2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-14970

Novus Biologicals, part of Bio-Techne
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NBP2-14970

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human GPS2. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

37 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for GPS2 Antibody

Western Blot: GPS2 Antibody [NBP2-14970]

Western Blot: GPS2 Antibody [NBP2-14970]

Western Blot: GPS2 Antibody [NBP2-14970] - Sample (30 ug of whole cell lysate) A: A431 B: HeLa 10% SDS PAGE, antibody diluted at 1:500.
Immunocytochemistry/ Immunofluorescence: GPS2 Antibody [NBP2-14970]

Immunocytochemistry/ Immunofluorescence: GPS2 Antibody [NBP2-14970]

Immunocytochemistry/Immunofluorescence: GPS2 Antibody [NBP2-14970] - HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: GPS2 protein stained by GPS2 antibody diluted at 1:500. Red: Phalloidin, a cytoskeleton marker, diluted at 1:200.
Immunohistochemistry-Paraffin: GPS2 Antibody [NBP2-14970]

Immunohistochemistry-Paraffin: GPS2 Antibody [NBP2-14970]

Immunohistochemistry-Paraffin: GPS2 Antibody [NBP2-14970] - Human gastric cancer, using GPS2 antibody at 1:500 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.

Applications for GPS2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: GPS2

This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq]

Alternate Names

AMF-1, G protein pathway suppressor 2, GPS-2, MGC104294, MGC119287, MGC119288, MGC119289

Gene Symbol

GPS2

Additional GPS2 Products

Product Documents for GPS2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GPS2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.