GRAIL/RNF128 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-13237

Novus Biologicals, part of Bio-Techne
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NBP2-13237
NBP2-13237-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (91%), Rat (92%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GRAIL/RNF128 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: HKTCVDPWLLEHRTCPMCKCDILKALGIEVDVEDGSVSLQVPVSNEISNSASSHEEDNRSETASSGYASVQGTDEPPLEEHVQSTNESLQLVNHEANSVAVDVIPHVDNPTFEEDETPNQETA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GRAIL/RNF128 Antibody

Immunohistochemistry-Paraffin: GRAIL/RNF128 Antibody [NBP2-13237]

Immunohistochemistry-Paraffin: GRAIL/RNF128 Antibody [NBP2-13237]

Immunohistochemistry-Paraffin: GRAIL/RNF128 Antibody [NBP2-13237] - Staining of human rectum shows moderate cytoplasmic positivity in glandular cells.

Applications for GRAIL/RNF128 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GRAIL/RNF128

The protein encoded by the RNF128 gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]

Long Name

Gene Related to Anergy in Lymphocytes Protein/Ring Finger Protein 128

Alternate Names

RNF128

Gene Symbol

RNF128

Additional GRAIL/RNF128 Products

Product Documents for GRAIL/RNF128 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for GRAIL/RNF128 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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