GRB7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1027

Novus Biologicals, part of Bio-Techne
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NB100-1027
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Key Product Details

Species Reactivity

Human

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all GRB7 Antibodies »

Product Specifications

Immunogen

Peptide with sequence ELDLSPPHLSSSPE-C corresponding to N-Terminus according to NP_005301.2.

Specificity

This antibody recognizes the longer isoform of this protein in A431 lysate.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for GRB7 Antibody

Western Blot: GRB7 Antibody [NB100-1027]

Western Blot: GRB7 Antibody [NB100-1027]

Western Blot: GRB7 Antibody [NB100-1027] - Antibody at 1ug/ml. Staining of A431 lysate (35u g protein in RIPA buffer). Detected by chemiluminescence.

Applications for GRB7 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:128000

Western Blot

1 - 3 ug/mL
Application Notes
Western blot: Approx 65 kDa band observed in lysates of cell line A431 (calculated MW of 59.7 kDa according to NP_005301.2).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: GRB7

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Alternative splicing results in multiple transcript variants encoding different isoforms, although the full-length natures of only two of the variants have been determined to date.

Long Name

Growth Factor Receptor-Bound Protein 7

Alternate Names

B47

Entrez Gene IDs

2886 (Human); 14786 (Mouse)

Gene Symbol

GRB7

UniProt

NP_005301. (Human)

Additional GRB7 Products

Product Documents for GRB7 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GRB7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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