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Gremlin 1 Antibody (D3)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-41969

Novus Biologicals, part of Bio-Techne
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NBP3-41969

Key Product Details

Species Reactivity

Human, Porcine

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # D3

Concentration

1 mg/ml

Product Specifications

Immunogen

Immunized with recombinant Human Gremlin 1 (Uniprot#: O60565; Lys26-Asp184 (Uniprot#: O60565)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Applications for Gremlin 1 Antibody (D3)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

5-20ug/mL

Immunohistochemistry

5-20ug/mL

Western Blot

0.5-2ug/mL
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

0.01M PBS, pH7.4, 50% glycerol

Preservative

0.05% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Gremlin

In Xenopus, Gremlin belongs to a novel gene family that act as BMP antagonists in embryonic explants. The human homolog of Drm/Gremlin (CKTFS1B1) is localized on human chromosome 15q13--> q15. DRM-specific mRNA is expressed in different human tissues, including brain, ovary, intestine and colon. It has been suggested that down-regulation of DRM is associated with tumor progression, and support the hypothesis that human DRM may play an important role during both neuroembryological development and carcinogenesis.

Alternate Names

DAND2, DRM, GREM1

Gene Symbol

GREM1

Additional Gremlin Products

Product Documents for Gremlin 1 Antibody (D3)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Gremlin 1 Antibody (D3)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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