GRF2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-13284

Novus Biologicals, part of Bio-Techne
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NBP3-13284
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GRF2 Antibodies »

Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GRF2. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Centrifuge briefly prior to opening.

Scientific Data Images for GRF2 Antibody

Western Blot: GRF2 Antibody [NBP3-13284]

Western Blot: GRF2 Antibody [NBP3-13284]

Western Blot: GRF2 Antibody [NBP3-13284] - Various whole cell extracts (30 ug) were separated by 5% SDS-PAGE, and the membrane was blotted with GRF2 antibody (NBP3-13284) diluted at 1:1000.
Immunohistochemistry-Paraffin: GRF2 Antibody [NBP3-13284]

Immunohistochemistry-Paraffin: GRF2 Antibody [NBP3-13284]

Immunohistochemistry-Paraffin: GRF2 Antibody [NBP3-13284] - GRF2 antibody detects GRF2 protein at cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded mouse muscle. GRF2 stained by GRF2 antibody (NBP3-13284) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
Immunohistochemistry-Paraffin: GRF2 Antibody [NBP3-13284]

Immunohistochemistry-Paraffin: GRF2 Antibody [NBP3-13284]

Immunohistochemistry-Paraffin: GRF2 Antibody [NBP3-13284] - GRF2 antibody detects GRF2 protein at cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded mouse heart. GRF2 stained by GRF2 antibody (NBP3-13284) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Applications for GRF2 Antibody

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GRF2

GRF2 encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq]

Alternate Names

C3GGRF2guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene), CRK SH3-binding GNRP, DKFZp781P1719, Guanine nucleotide-releasing factor 2, Protein C3G, Rap guanine nucleotide exchange factor (GEF) 1, rap guanine nucleotide exchange factor 1

Gene Symbol

RAPGEF1

Additional GRF2 Products

Product Documents for GRF2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GRF2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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