GRID2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-31723

Novus Biologicals, part of Bio-Techne
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NBP2-31723
NBP2-31723-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (98%), Rat (98%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GRID2 Antibodies »

Product Summary for GRID2 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: AVYEHVRMKGLNPFERDSMYSQMWRMINRSNGSENNVLESQAGIQKVKYGNYAFVWDAAVLEYVAINDPDCSFYTIGNTVADR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GRID2 Antibody

Immunohistochemistry-Paraffin: GRID2 Antibody [NBP2-31723]

Immunohistochemistry-Paraffin: GRID2 Antibody [NBP2-31723]

Immunohistochemistry-Paraffin: GRID2 Antibody [NBP2-31723] - Staining of human testis shows high expression.
Immunohistochemistry-Paraffin: GRID2 Antibody [NBP2-31723]

Immunohistochemistry-Paraffin: GRID2 Antibody [NBP2-31723]

Immunohistochemistry-Paraffin: GRID2 Antibody [NBP2-31723] - Staining of human cerebellum shows distinct positivity in neuropil of the molecular layer.
Immunohistochemistry-Paraffin: GRID2 Antibody [NBP2-31723]

Immunohistochemistry-Paraffin: GRID2 Antibody [NBP2-31723]

Immunohistochemistry-Paraffin: GRID2 Antibody [NBP2-31723] - Staining of human endometrium shows low expression as expected.
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Applications for GRID2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GRID2

Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamategated, cation-specific ion channels. Kainate/AMPA receptors co-localize with NMDA receptors in many synapses and consist of seven structurally related subunits, designated GluR-1 to -7, as well as GluR-delta2. The kainate/AMPA receptors are primarily responsible for the fast excitatory neurotransmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: episilon1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem whereas the four episilon subunits display limited distribution. In mice, mutations in the gene encoding GluR-delta2 (GRID2) cause the Lurcher phenotype. The gene encoding human GluR-delta2 maps to chromosome 4q22.

Long Name

Glutamate Receptor, Ionotropic, Delta 2

Alternate Names

GLURD2, GluRdelta2, Ms10ac, SCAR18

Gene Symbol

GRID2

UniProt

O43424 (Human)

Additional GRID2 Products

Product Documents for GRID2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for GRID2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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