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GRK2 Antibody (S01-6I5)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-20067

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-20067-100ul
NBP3-20067-50ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S01-6I5

Concentration

0.3 mg/ml

Product Summary for GRK2 Antibody (S01-6I5)

Immunogen

A synthetic peptide of human GRK2 (Uniprot # P25098)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

80 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for GRK2 Antibody (S01-6I5)

Western Blot: GRK2 Antibody (S01-6I5) [NBP3-20067]

Western Blot: GRK2 Antibody (S01-6I5) [NBP3-20067]

Western Blot: GRK2 Antibody (S01-6I5) [NBP3-20067] - Western blot detection of GRK2 in Hela, A549, HL-60, U2OS cell lysates using NBP3-20067 (1:1000 diluted). Predicted band size: 80kDa. Observed band size: 80kDa.

Applications for GRK2 Antibody (S01-6I5)

Application
Recommended Usage

Western Blot

1/1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GRK2

Adrenergic Receptor beta Kinase 1 (ADRBK1), also known as GRK2, is a member of the G-protein receptor kinase family. A ubiquitous cytosolic enzyme, GRK-2 specifically phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed under high agonist concentrations. Defects in GRK2 coupling with G-protein receptors may lead to heart failure.

Long Name

G protein-coupled Receptor Kinase 2

Alternate Names

ADRBK1, BARK1, Beta-ARK1

Gene Symbol

GRK2

Additional GRK2 Products

Product Documents for GRK2 Antibody (S01-6I5)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GRK2 Antibody (S01-6I5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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