Growth Hormone R Antibody (S02-6E6)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19651

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-19651-100ul
NBP3-19651-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S02-6E6

Concentration

0.3 mg/ml

View all Growth Hormone R/GHR Antibodies »

Product Summary for Growth Hormone R Antibody (S02-6E6)

Immunogen

A synthetic peptide of human Growth Hormone R (Uniprot # P10912)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

120 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Growth Hormone R Antibody (S02-6E6)

Western Blot: Growth Hormone R Antibody (S02-6E6) [NBP3-19651]

Western Blot: Growth Hormone R Antibody (S02-6E6) [NBP3-19651]

Western Blot: Growth Hormone R Antibody (S02-6E6) [NBP3-19651] - Western blot detection of Growth Hormone R in Rat Brain lysates using NBP3-19651 (1:500 diluted). Predicted band size: 72kDa. Observed band size: 120kDa.

Applications for Growth Hormone R Antibody (S02-6E6)

Application
Recommended Usage

Western Blot

1/1000-1/5000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Growth Hormone R/GHR

Growth hormone receptor encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. Other splice variants, including one encoding a soluble form of the protein (GHRtr), have been observed but have not been thoroughly characterized.

Long Name

Growth Hormone Receptor

Alternate Names

GHR

Gene Symbol

GHR

Additional Growth Hormone R/GHR Products

Product Documents for Growth Hormone R Antibody (S02-6E6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Growth Hormone R Antibody (S02-6E6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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